Can I be allergic to pre-wrap?

Underwrap known as m-wrap from Mueller is a latex-free product. According to sources at Mueller, they've done investigations into skin irritations from taping. What they have learned is that skin irritations occur not from the pre-wrap itself but rather
from either a.) other products like sprays or ointments used while
taping or b.) occlusion of the skin that has not been cleansed can
result in a form of heat rash. This is itchy and often painful.

M-wrap is a polyester polyurethane foam, which is inert.
Preliminary repeated insult patch testing show no hypersensitivity in
humans to the foam. It is a petroleum product, so people can react to
this similar to neoprene, in rare cases.

This is not to be construed as medical advice. Please check with your doctor if you
are concerned about any reaction you have.